Octavian Bucur
Instructor
BIDMC, Harvard Medical School
USA
Biography
Octavian Bucur, MD, PhD is Instructor in the Department of Pathology at the Harvard Medical School and Beth Israel Deaconess Medical Center, in Boston, MA, focusing on the development and application of new experimental and computational technologies with significant impact in molecular, diagnostic pathology and personalized medicine. He is also a member of the Ludwig Cancer Center at Harvard and Broad Institute of MIT and Harvard. In collaboration with Dr. Edward Boyden’s laboratory at MIT, he has developed a pathology-optimized physical tissue expansion method called Expansion Pathology, that enables~100 times expansion in volume of any type of clinical specimen and visualization of 70-80nm structures with conventional optical microscopes (currently limited to ~250nm resolution). Expansion Pathology has the potential of replacing electron microscopy in diagnosis and investigation of certain pathologies and nanometer structures (Nature Biotechnology, August 2017, 3 patents filed).
Research Interest
He has developed a pathology-optimized physical tissue expansion method called Expansion Pathology, that enables~100 times expansion in volume of any type of clinical specimen and visualization of 70-80nm structures with conventional optical microscopes (currently limited to ~250nm resolution). Expansion Pathology has the potential of replacing electron microscopy in diagnosis and investigation of certain pathologies and nanometer structures (Nature Biotechnology, August 2017, 3 patents filed).