Biography
Yiu-Lian is the Innovation Lead for Diagnostics, at Johnson & Johnson Innovation, London. Prior to joining Johnson & Johnson Innovation, Yiu-Lian was Divisional Vice President for R&D at Abbott Molecular. In this position, she was responsible for R&D strategic oversight, menu expansion, and the development of next generation molecular diagnostic platform technologies. Previously, she was the Executive Director of Molecular Diagnostics and Companion Diagnostics Development at Novartis Oncology. Yiu-Lian brings a broad and extensive background in the pharmaceutical and biotechnology industries including experience in technology and product development, blood testing/screening, vaccines and IVD Immuno and molecular diagnostics, as well as therapeutic drug/vaccine development.
Research Interest
•Develop and/or execute business strategies for genetics, oncology, infectious disease, metabolic disease, and neuroscience •Develop and drive technical strategies for drug and companion diagnostics co-development • Recruit and develop talents, build functional departments and project teams, develop and implement product development and project management tools and processes, grow organization. • Direct, manage and oversee R&D functions for biological drug and vaccine development, blood screening, and IVD product development: Biomarker Development, Assay Development, System and SW Engineering, System Integration, Design Transfer, Technology Transfer, Technology Development, Process Development and Validation, Pilot Production, Analytical Method Development and Method Validation, QC Testing, Project Management (PMO) and Scientific Affairs. •Drug development CMC lead or core team member: Phase I, II and III IND, and NDA/BLA submissions for biological and blood screening. •Technology assessments and strategic alignment for M&A and BDL initiatives •Strategic alliance with partners and vendors, drive and manage collaborations
Biography
Dr. Leyla B. Djansugurova is a Full Professor of Genetics, PhD. Current position - General Director of the Institute of General Genetics and Cytology (Almaty, Republic of Kazakhstan). She specialized in cytogenetics, molecular genetics, and cell biology. Training and research experience: Department of genetics, Moscow State University named M.Y. Lomonosov; Institute of molecular genetics RAS, Moscow, Russia; Institute of Gene Biology RAS, Moscow, Russia; Department of genetics, Leicester University, Leicester, Great Britain.
Research Interest
Dr. Leyla B. Djansugurova’s research interests: Drosophila genetics, Human genetics, genetic instability, apoptosis; individual susceptibility and resistance to cancer and hazard environmental influence; cancer genetics, and genetics of ageing. She is an independent expert in the field of DNA fingerprinting. Leyla Djansugurova was an executor of 2 international grants, and 11 Kazakhstan research projects were done under her leadership. In total she has 236 papers, 5 workbooks, 2 monographs, 3 patents. There are 7 PhD research works were done under her supervising, currently 3 PhD students are being prepared. Twice she has been awarded by governmental awards for her contribution to science. Her activities in cancer research were related to oncovirus-induced mutagenesis, elucidation the role of apoptotic key genes in development of cervical and esophageal cancers, the lectin based approach to early detection of cancer cells, the molecular epidemiology of sporadic and inherited forms of cervical, esophageal and colorectal cancers.
Biography
Since 1988 Dr. Kuppen is connected with Leiden University Medical Centre. As researcher at the Department of Pathology in 1993 he defended his thesis \\\"Studies on interleukin-2-activated rat natural killer cells. Establishment of a syngeneic model for adoptive immunotherapy of cancer\\\'\\\'. He became researcher and Head of the research group \\\'Immunotherapy of cancer\\\' at the Department of Surgery. In 2001 Dr. Kuppen became head of the Laboratory for Surgical Oncology and in 2009 Head of the Research Laboratory for Surgery. Besides a researcher Dr. Kuppen is coordinator of the program for academic training of the study Biomedical Sciences.
Research Interest
His Research interests as a project leader in research surgical oncology are Immunotherapy colorectal cancer and Diagnostic and prognostic factors for colon and breast cancers. He is an expert on cancer immunotherapy, focused on colorectal cancer and prognostic and predictive biomarkers in colorectal and breast cancer.